Paris — On February seventeenth, 2021, Philip Morris Worldwide (PMI) held a web based occasion entitled ” Can scientifically substantiated smoke-free merchandise contribute to public well being outcomes?”. This occasion was the third of its « Open Science Convention sequence » aimed toward discussing and sharing the newest scientific information round tobacco and smoke-free merchandise, and in addition elementary ideas behind their analysis “in an open and clear method” because the host, Gizelle Baker, stated. She is the VP, World Scientific Engagement at PMI. Baker is an epidemiologist and biostatistician by coaching and has labored on medical analysis for 20 years. She particularly works on hurt discount and the science behind smoke-free merchandise. For her, science, and solely science, ought to prevail over another subject.
Her assertion was as follows: ” It’s our duty to transparently share our analysis and information with governments, authorities, organizations, and the general public to encourage dialogue and debate on tobacco hurt discount that’s rooted in science. As a result of It is vital that science is on the heart of any dialogue on well being and coverage selections. People who smoke and society extra typically predict that scientists, regulators, public well being and trade are working collectively to seek out options that may assist cut back smoking and extra exactly, smoking-related loss of life and illness.”
In actual fact, PMI has designed a smoke-free inhaled nicotine aerosol, underneath the model identify IQOS. This tobacco heating system (THS) heats tobacco somewhat than burning it. It’s at present offered in 64 markets world wide. Current research and the Meals and Drug Administration (FDA) just lately declared IQOS as probably much less dangerous than typical cigarettes:
” The toxicological evaluation additionally discovered that, in contrast with cigarette smoke, IQOS aerosols include significantly decrease ranges of potential carcinogens and poisonous chemical compounds that may hurt the respiratory or reproductive programs…Knowledge submitted by the corporate exhibits that advertising these explicit merchandise with the approved info may assist addicted grownup people who smoke transition away from combusted cigarettes and cut back their publicity to dangerous chemical compounds, however provided that they utterly swap ,” stated the FDA in July 2020.
Furthermore, based on current information given by Gizelle Baker , there are greater than 17 million IQOS customers globally and 12.7 million have utterly cease ped smoking cigarettes. Because of this 72% of IQOS customers not smoke cigarettes. Baker states that she has little doubt that smoke-free merchandise like IQOS can contribute to public well being.
Mikael Franzon additionally contributed to this occasion. He’s a psychologist by coaching with a Ph.D. in Neuroscience. He labored for the pharmaceutical trade earlier than beginning to collaborate with PMI 5 years in the past. It’s his opinion that smoke-free options are important to public well being:
” Research have proven over time that combustion and publicity to toxicants are liable for smoke-related ailments and loss of life…In different phrases, we may complement current tobacco management methods for people who smoke who would in any other case proceed to smoke by selling switching to much less dangerous options. In case you do not stop, change.” He pleads for pragmatism to enhance particular person and public well being. He acknowledged that ” By definition, the perfect factor a smoker can do to cut back this danger of creating a smoking-related illness, is to stop tobacco and nicotine altogether. However everyone knows that many will not.”
Dr. Andrea Costantini is Head of Regional Scientific Engagement Latin America & Canada. She is a medical physician specialised in medical pharmacology. She introduced a current research led by PMI on the occasion. On this research ( charts available in this presentation – at 5 minutes ), consultants divided grownup people who smoke into three teams to look at over 90 days: These within the first group continued to smoke for the interval, these in the second stop smoking in the course of the research, and people within the final group switched to heated tobacco programs. Over a interval of 90 days, they measured participant’s publicity to fifteen chosen dangerous chemical compounds corresponding to carbon monoxide, acrolein, and nitrosamines, amongst others. Andrea Costantini introduced the conclusion of this research:
” This research exhibits that switching utterly to our heated tobacco system achieves nearly 95% of the discount in publicity that’s achieved by smoking abstinence. As soon as once more, a number of internationally acknowledged consultants help our findings such because the U.S. Meals and Drug Administration, the German Federal Institute for Threat Evaluation, Public Well being England amongst others.”
She continues to state: “The totality of the obtainable proof at this time strongly signifies that switching to our heated tobacco system, though it’s not risk-free, is a a lot better different than persevering with to smoke for these grownup people who smoke who in any other case would preserve smoking.”
SteveRoulet, who leads the event and execution of PMI’s shopper analysis research on smoke-free merchandise, corroborated the arguments via a selected case. He, in actual fact, used the instance of Japan, which is the nation with the best prevalence of heated tobacco merchandise on this planet. Additionally it is the nation the place IQOS was first launched in 2014. Additionally, Japan is among the few nations, the place the general public well being authorities have just lately began measuring the prevalence of cigarette smoking individually from using heated tobacco merchandise:
” The information from the federal government’s Nationwide Well being and Diet Survey present that whereas the pattern within the total prevalence of tobacco use in Japan stays unchanged, the introduction of heated tobacco merchandise within the Japanese market in 2014 – which have been measured for the primary time within the nationwide survey individually from cigarettes in 2018 – seems to have contributed to the accelerated decline in flamable cigarette smoking. In actual fact, Japan’s smoking fee is now among the many lowest within the developed world.” based on Roulet.
He concluded that ” the THS has the potential to transition many grownup people who smoke away from flamable cigarette use, which is essentially the most dangerous use of tobacco. These transition patterns are beginning to emerge at a inhabitants degree in Japan, the nation with the best prevalence of heated tobacco product use to this point”.
In Africa, the one tobacco heating system obtainable to this point is IQOS. It’s offered in just one market – South Africa. On the continent, there are not any research obtainable but on the potential connection between public well being and people heating programs as options to cigarettes.